It has been shown time and again that the Canon EOS 5D Mark II and other Canon cameras perform better at the following ISO settings: 160, 320, 640, 1250, 3200 when shooting video. These are multiples of 160.

Tho – to be sure, you should do your own testing. Most of these tests were done with the lens cap on and then the noise was exaggerated to make the evaluations… most people won’t be shooting in that much dark.

The problem is, as the ISO gets higher, the dynamic range decreases drastically. The challenge thus is to find the balance between low noise and proper dynamic range to preserve the highlights.

So watch the histogram carefully before pressing the record button, you dont want to have anything blown out!

As a rule of thumb, if you keep the ISO under 800 the loss in dynamic range is relatively minimal but at 800+, it goes down drastically. Then again, you are better off with a clip with blown highlights than nothing, so sometimes you have to get more light in.

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